| Matches by round |
| 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 |
| Match list: | By round By date Latest | Player stats: |
| R | Date | Home | Score | Away | Location | |
| 1 | 11/10/2009 | Sirens | 1 - 3 | Sta. Lucia | Centenary Stadium | |
| 2 | 26/10/2009 | Sta. Lucia | 2 - 4 | Naxxar L. | Centenary Stadium | |
| 3 | 19/11/2009 | Gudja U. | 0 - 0 | Sta. Lucia | Centenary Stadium | |
| 4 | 27/11/2009 | Sta. Lucia | 0 - 1 | Xghajra T. | Centenary Stadium | |
| 5 | 08/12/2009 | Sta. Lucia | 0 - 0 | Kirkop U. | Centenary Stadium | |
| 6 | 20/12/2009 | Zejtun C. | 5 - 0 | Sta. Lucia | Centenary Stadium | |
| 7 | 10/01/2010 | Sta. Lucia | 0 - 4 | Swieqi U. | Centenary Stadium | |
| 8 | 18/01/2010 | Qrendi | 1 - 2 | Sta. Lucia | Centenary Stadium | |
| 9 | 29/01/2010 | Sta. Lucia | 0 - 1 | Attard | Centenary Stadium | |
| 10 | 12/02/2010 | Sta. Lucia | 1 - 0 | Sirens | Centenary Stadium | |
| 11 | 22/02/2010 | Naxxar L. | 1 - 0 | Sta. Lucia | Centenary Stadium | |
| 12 | 05/03/2010 | Sta. Lucia | 0 - 2 | Gudja U. | Centenary Stadium | |
| 13 | 14/03/2010 | Xghajra T. | 1 - 0 | Sta. Lucia | Centenary Stadium | |
| 14 | 28/03/2010 | Kirkop U. | 3 - 1 | Sta. Lucia | Centenary Stadium | |
| 15 | 11/04/2010 | Sta. Lucia | 1 - 3 | Zejtun C. | Centenary Stadium | |
| 16 | 25/04/2010 | Swieqi U. | 3 - 1 | Sta. Lucia | Centenary Stadium | |
| 17 | 07/05/2010 | Sta. Lucia | 3 - 4 | Qrendi | Centenary Stadium | |
| 18 | 16/05/2010 | Attard | 1 - 2 | Sta. Lucia | Centenary Stadium |