| Matches by round |
| 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 |
| Match list: | By round By date Latest | Player stats: |
| R | Date | Home | Score | Away | Location | |
| 1 | 26/09/2010 | Naxxar L. | 0 - 1 | Zejtun C. | Centenary Stadium | |
| 2 | 03/10/2010 | Mellieha | 0 - 1 | Naxxar L. | Centenary Stadium | |
| 3 | 15/10/2010 | Naxxar L. | 3 - 2 | Mgarr U. | Centenary Stadium | |
| 4 | 23/10/2010 | Gzira U. | 3 - 2 | Naxxar L. | Centenary Stadium | |
| 5 | 31/10/2010 | Naxxar L. | 4 - 0 | San Gwann | Centenary Stadium | |
| 6 | 13/11/2010 | Senglea A. | 2 - 3 | Naxxar L. | Centenary Stadium | |
| 7 | 21/11/2010 | Naxxar L. | 0 - 1 | Rabat A. | Centenary Stadium | |
| 8 | 12/12/2010 | St. Patrick | 3 - 0 | Naxxar L. | Centenary Stadium | |
| 9 | 18/12/2010 | Naxxar L. | 4 - 1 | Birzebbuga SP | Centenary Stadium | |
| 10 | 02/01/2011 | Zebbug R. | 2 - 3 | Naxxar L. | Centenary Stadium | |
| 11 | 09/01/2011 | Naxxar L. | 3 - 2 | Zurrieq | Centenary Stadium | |
| 12 | 22/01/2011 | Zejtun C. | 0 - 0 | Naxxar L. | Centenary Stadium | |
| 13 | 29/01/2011 | Naxxar L. | 2 - 0 | Mellieha | Centenary Stadium | |
| 14 | 05/02/2011 | Mgarr U. | 2 - 1 | Naxxar L. | Centenary Stadium | |
| 15 | 13/02/2011 | Naxxar L. | 3 - 0 | Gzira U. | Centenary Stadium | |
| 16 | 26/02/2011 | San Gwann | 0 - 0 | Naxxar L. | Centenary Stadium | |
| 17 | 06/03/2011 | Naxxar L. | 4 - 0 | Senglea A. | Centenary Stadium | |
| 18 | 13/03/2011 | Rabat A. | 2 - 0 | Naxxar L. | Centenary Stadium | |
| 19 | 31/03/2011 | Naxxar L. | 2 - 2 | St. Patrick | Centenary Stadium | |
| 20 | 09/04/2011 | Birzebbuga SP | 1 - 5 | Naxxar L. | Centenary Stadium | |
| 21 | 16/04/2011 | Naxxar L. | 3 - 2 | Zebbug R. | Centenary Stadium | |
| 22 | 30/04/2011 | Zurrieq | 0 - 0 | Naxxar L. | Centenary Stadium |