| Date | Match | Result | Scorers |
| 02-Sep | Nadur Y. vs Xaghra U. | 4-1 | Brandon Said (2), Stefan Cassar (2)(N); Johann Bajada (X) |
| 03-Sep | Mellieha vs Munxar F. | 4-3 | Bryan Bautista (2), Jeffrey Gauci, own goal (Mel); Mattias Michael Uzor, Jordi Parnis (2)(Mun) |
| 03-Sep | Oratory Y. vs Ghaxaq | 4-0 | Bartomeu Perello Palou (2), Ralph Ebube Okpokwu (2) |
| 03-Sep | Xewkija T. vs Marsaskala | 4-1 | Thiago Melo dos Santos (2), Rodney Buttigieg, Joseph George Vella (X); Matthew Gauci (M) |
| 03-Sep | Xghajra T. vs St. Laurence S. | 4-1 | Emre Yener (3), Royter Degiorgio (X); Denis Di Maio (SL) |
| Date | Match | Result | Scorers |
| 10-Sep | Mdina K. vs Mellieha | 2-3 | own goal, Samuel Bartolo (MK); Bryan Rene Bautista Navarro, Kyle Simiana (2) (Mel) |
| 11-Sep | Xghajra T. vs Msida SJ | 2-1 | own goal, Gabriel Bonavia (X); Dylan Agius (M) |
| 08-Sep | Oratory vs Kercem A. | 4-4 aet (1-4 pen) | Ralph Ebube Okpokwu, Bartomeu Perello Palou, Joshua Buttigieg (2)(O); Ognjen Rolovic, Alen Haska, Nathaniel Mercieca, Jean Paul Mizzi (K) |
| 10-Sep | Victoria H. vs Nadur Y. | 2-0 | John Camilleri, Elton da Silva |
| 10-Sep | Mtarfa vs Dingli S. | 1-3 | Paul Azzopardi (M); Peter Andrejco, Karl Cilia, Dylan Camenzuli (D) |
| 09-Sep | Ta’ Xbiex vs Sta. Venera L. | 1-4 | Luca Bugeja, Eddie Wileman (3) (SV); Riccardo Napoli (TX) |
| 20-Sep | Ghajnsielem vs Kirkop U. | 2-2 aet (8-7 pen) | Neil Cutajar, Michael Theuma (K); Alberto Xuereb, Shaun Bajada (Gh) |
| 09-Sep | Zurrieq vs Qala S. | 3-1 | Daniel Zammit, Leontiev Konda, Gilbert Camilleri (Z); Joseph Buttigieg (Q) |
| 10-Sep | SK Victoria W. vs Xewkija T. | 1-4 | own goal, Gennaro Hili, Rodney Buttigieg, Thiago Melo dos Santos (X); Nicolas Abot (SKV) |
| Date | Match | Result | Scorers |
| 22-Oct | Pembroke A. vs Pietà H. | 1-3 | Caio Alves De Souza (PA); Clive Gauci (3)(PH) |
| 21-Oct | Gharghur vs Vittoriosa S. | 1-7 | Joseph Jojo Ogunuppe, Obinna Obiefule (2), Andre Farrugia (2), Christian Suarez Leon, Armand Leilis |
| 21-Oct | Marsaxlokk vs Zabbar SP | 5-0 | Kenneth Ekezie, Alan Tabone (3), Cleaven Jeffrey Zammit |
| 22-Oct | Zurrieq vs Qrendi | 1-3 | Shunsuke Nakamura, Dhonathan Santos da Hora (2) (Q); Gilbert Camilleri (Z) |
| 22-Oct | Gudja U. vs Rabat A. | 3-0 aet | Nicholas Zammit (2), Jean Claud Cesare |
| 21-Oct | Sirens vs Zebbug R. | 1-3 | Clifford Gauci, Aleksandar Kovacic (2)(Z); Darko Medic (S) |
| 22-Oct | Xewkija T. vs Xghajra T. | 5-2 | Joseph George Vella, Claudio Antunes (2), Thiago Melo dos Santos, Milos Stojanovic (Xewk); Royter Degiorgio (2)(Xgh) |
| 21-Oct | Fgura U. vs Qormi | 1-4 | Tensior Gusman, Julien Salaroli, Lubos Adamec, Jose Lucas Caetano da Silva (Q); Thomas Grech (F) |
| 22-Oct | Mgarr U. vs Mqabba | 0-3 | Paul Chimezie (2), Tomislav Trebovac |
| 22-Oct | Marsa vs Santa Lucia | 1-4 | Santiago Solano Rodriguez (2), Sebastian Perdomo (2)(SL); own goal (M) |
| 21-Oct | Sta. Venera L. vs Kalkara | 1-2 | Timothy Thomas, Dylan Xuereb (K); Joel Winters (SV) |
| 21-Oct | Zejtun C. vs Dingli S. | 5-0 | Luis de Melo Lima (2), Adrian Carabott, Ryan Cauchi, Saturday Nanapere |
| 21-Oct | Mellieha vs Swieqi U. | 1-2 | Roderick Taliana, Mirco Vella (S); Bryan Bautista (M) |
| 22-Oct | San Gwann vs St. George’s | 2-0 | Mario Andres Artieta Suarez, Joao Claudio Kiala |
| 22-Oct | Victoria H. vs Birzebbuga SP | 4-0 | Elton Alexandre da Silva, Chris Camilleri, Henrique Maciel, Andrea Debrincat |
| 22-Oct | Attard vs Kercem A. | 0-2 aet | Ognjen Rolovic, Alen Haska |
| 21-Oct | Siggiewi vs Luqa SA | 4-2 | Alan Abdel Rahman, own goal (L); Jake Vella, Ian Montanaro, Mauro Busuttil (2)(S) |
| 22-Oct | Melita vs Ghajnsielem | 3-3 aet (4-2 pen) | Everton Felipe da Silva, Oscar Guerrero (2)(Gh); Luke Mifsud, Nicholas Bradshaw, Luke Micallef (M) |
| Date | Match | Result | Scorers |
| 02-Dec | Balzan vs Gudja U. | 4-1 | Bojan Kaljevic, Marko Platisa, Alex da Paixao Alves (2)(B); Chris Grech (G) |
| 02-Dec | Santa Lucia vs Birkirkara | 0-5 | Luke Montebello (3), Jake Grech, Gianluca Zammit |
| 02-Dec | Valletta vs Senglea A. | 2-0 | Raed Ibrahim Saleh, Michael Mifsud |
| 02-Dec | Naxxar L. vs Floriana | 3-1 aet | Scott James Fenwick (2), Yuri de Jesus Messias (N); Mario Fontanella (F) |
| 02-Dec | Hibernians vs Victoria H. | 2-1 | own goal, Johann Bezzina (H); Elton Alexandre da Silva (V) |
| 02-Dec | St. Andrews vs Sliema W. | 1-3 | Kevaughn Atkinson (SA); Nicolae Milinceanum, Frank Temile, Jefferson de Assis Estacio |
| 01-Dec | Lija A. vs Kalkara | 4-0 | Raphael Kooh Sohna (3), Abubakar Bello Osagie |
| 03-Dec | Xewkija T. vs Vittoriosa S. | 4-0 | Rodney Buttigieg, Claudio Antunes (2), Joseph Mario Vella |
| 01-Dec | San Gwann vs Melita | 3-0 | Daniel Chavez Flores (2), Jan Tanti |
| 03-Dec | Qrendi vs Qormi | 2-0 | Dhonathan Santos da Hora, Petar Mrvic |
| 03-Dec | Kercem A. vs Zebbug R. | 5-1 | Andrew Mizzi (2), Jean Paul Mizzi, Ognjen Rolovic, Aleksandar Komljenovic (K); Rafael da Silva Gomes (Z) |
| 03-Dec | Marsaxlokk vs Zejtun C. | 0-3 | Luis Andre de Melo Lima (2), Miguel Ciantar |
| 01-Dec | Siggiewi vs Pietà H. | 2-3 aet | Juan Manuel Artiaga Roa, Gabriel Mensah, Jan Busuttil (P); Eman Ciappara, Trayo Grozev (S) |
| 01-Dec | Mosta vs Mqabba | 2-1 | Edison Bilbao Zarate, Tyrone Farrugia (Mos); Michael Borg (Mqa) |
| 03-Dec | Gzira U. vs Hamrun S. | 0-1 aet | Tiago Souza da Silveira |
| 03-Dec | Swieqi U. vs Tarxien R. | 0-3 | Matar Dieye (2), Matthew Brincat |
| Date | Match | Result | Scorers |
| 20-Jan | Tarxien R. vs Lija A. | 1-2 | Ricardo Silva Faria (T); Ousmane Sidibe Erjon Beu (L) |
| 20-Jan | Kercem A. vs Qrendi | 3-4 aet | Ognjen Rolovic (2), Alen Haska (K); Julio Cesar da Souza Martins (2), Dhonathan Santos da Hora, Aaron Agius (Q) |
| 21-Jan | Hibernians vs Xewkija T. | 3-0 | João Vítor Rocha de Carvalho Moreira, Jurgen Degabriele (2) |
| 20-Jan | Balzan vs Naxxar L. | 2-0 | Alex da Paixao Alves (2) |
| 21-Jan | Pietà H. vs Valletta | 0-1 | Ryan Camilleri |
| 20-Jan | Hamrun S. vs Sliema W. | 0-1 | Goran Adamovic |
| 20-Jan | Mosta vs Zejtun C. | 1-2 | Adam Smeir, Johan Castano (Z); Leonardo Henrique Ferreira (M) |
| 19-Jan | Birkirkara vs San Gwann | 2-1 aet | Godwin Blessing Henshaw (SG); Fernando Barbosa Pereira, Carlos Alberto da Silva Goncalves Junior (B) |
| Date | Match | Result | Scorers |
| 17-Feb | Hibernians vs Sliema W. | 0-0 aet (1-4 pen) | |
| 17-Feb | Qrendi vs Birkirkara | 0-3 | Cain Attard, Nikola Vukanac, Edward Herrera |
| 17-Feb | Valletta vs Zejtun C. | 2-0 | Kyrian Nwoko, Steve Borg |
| 17-Feb | Lija A. vs Balzan | 1-3 | Carlos Eduardo de Fiori Mendes (2), Uros Ljubomirac (B); Aaron Sammut (L) |
| Date | Match | Result | Scorers |
| 28-Apr | Birkirkara vs Sliema W. | 1-1 aet (3-2 pen) | Ognjen Rolovic (B); Frank Temile (S) |
| 29-Apr | Valletta vs Balzan | 2-1 | Alex da Paixao Alves (B); Denni Rocha dos Santos, Matteo Piciollo (V) |
| Date | Match | Result | Scorers |
| 05-May | Birkirkara vs Valletta | 1-2 | Kyrian Nwoko, Santiago Malano (V); Ognjen Rolovic (B) |