| Date | Home | vs | Away | Result | Scorers |
| 26-Oct | Melita | vs | Hamrun S. | 4-2 | Timothy Portelli, Beppe Amato Gauci, Mark Peresso Sammut (2)(M); Zak Barbara, Felippe Bugeja (H) |
| 26-Oct | Zabbar SP | vs | Pieta' H. | 0-2 | Kian Leonardi, Marco Cassara |
| 27-Oct 09-Nov | Floriana | vs | San Gwann | 0-0 | |
| 27-Oct | Mosta | vs | St. Andrews | 1-0 | own goal |
| 02-Nov | Mosta | vs | Floriana | 1-1 | Matthias Said (M); Raul Formosa (F) |
| 02-Nov | Melita | vs | Zabbar SP | 1-0 | Matthew Sciberras |
| 02-Nov | Hamrun S. | vs | San Gwann | 3-0 | Zak Barbara, Ensell Attard (2) |
| 03-Nov | St. Andrews | vs | Pieta' H. | 2-3 | Ivin Farrugia, Edward Lee Agius, Marco Cassara (P); Matthias Pace, Timothy Cassar Torregiani (SA) |
| 16-Nov | Pieta' H. | vs | Hamrun S. | 0-2 | Kian Vella, Sven Xerri |
| 16-Nov | Zabbar SP | vs | St. Andrews | 0-3 | Sean Gatt (3) |
| 17-Nov | Floriana | vs | Melita | 0-1 | Beppe Amato Gauci |
| 17-Nov | San Gwann | vs | Mosta | 0-0 | |
| 23-Nov | San Gwann | vs | St. Andrews | 1-2 | Sean Gatt, Matthias Pace (SA); Jean Micallef (SG) |
| 23-Nov | Hamrun S. | vs | Zabbar SP | 4-0 | Felippe Bugeja, Trezeguet Zammit, Ensell Attard, Sven Xerri |
| 24-Nov | Pieta' H. | vs | Floriana | 4-0 | Ivin Farrugia, Kian Leonardi (2), Edward Lee Agius |
| 24-Nov | Mosta | vs | Melita | 1-0 | Russel Caruana |
| 14-Dec | Zabbar SP | vs | Mosta | 0-4 | Leo Perkins, Matthias Said, Russel Caruana (2) |
| 15-Dec | Floriana | vs | Hamrun S. | 0-4 | Sven Xerri, Enell Attard (2), Sean Agius |
| 15-Dec | St. Andrews | vs | Melita | 0-0 | |
| 15-Dec | San Gwann | vs | Pieta' H. | 1-2 | Marco Cassara, Aiden Zammit (P); Myron Micallef (SG) |
| 04-Jan | Hamrun S. | vs | St. Andrews | 7-2 | Sven Xerri, Felippe Bugeja, Ensell Attard (3), Zak Barbara, Trezeguet Zammit (H); Sean Gatt, Timothy Cassar Torregiani (SA) |
| 04-Jan | Zabbar SP | vs | Floriana | 0-0 | |
| 11-Jan | Melita | vs | San Gwann | 1-1 | Myron Micallef (SG); Oliver Rocco Naudi (M) |
| 12-Jan | Mosta | vs | Pieta' H. | 2-1 | Kian Leonardi (P); Nicholas Strickland (2)(M) |
| 18-Jan | Pieta' H. | vs | Melita | 1-2 | Daniel Sciberras Timothy Portelli (M); Kian Leonardi (P) |
| 19-Jan | Floriana | vs | St. Andrews | 0-2 | Timothy Cachia, Mike Hudson |
| 19-Jan | Hamrun S. | vs | Mosta | 1-0 | Felippe Bugeja |
| 19-Jan | San Gwann | vs | Zabbar SP | 2-1 | Tyron Caruana (Z); Jack Vella, Xylen Debono Refalo (SG) |
| 01-Feb | San Gwann | vs | Floriana | 4-0 | Jean Micallef, Zen Falzon, Matthias Fenech, Colin Sammut |
| 01-Feb | Hamrun S. | vs | Melita | 0-2 | Travis Vella, Timothy Portelli |
| 02-Feb | St. Andrews | vs | Mosta | 2-2 | Sean Gatt (2)(SA); Russel Caruana (2)(M) |
| 09-Feb | Pieta’ H. | vs | Zabbar SP | 5-1 | Thomas Howland, Ivin Gatt, Kian Leonardi (2), Edward Lee Agius (P); Klajdi Cassar (Z) |
| 15-Feb | Floriana | vs | Mosta | 2-3 | Christopher Buttigieg, Jeancole Attard (F); Nicholas Strickland, Mason Agius, Russel Caruana (M) |
| 15-Feb | Zabbar SP | vs | Melita | 1-1 | Matthew Sciberras (M); Cheyzen Spagnol (Z) |
| 16-Feb | San Gwann | vs | Hamrun S. | 0-1 | Zak Barbara |
| 16-Feb | Pieta' H. | vs | St. Andrews | 4-3 | Sean Gatt (2), Matthias Pace (SA); Ivin Gatt, Kian Leonardi, Aiden Zammit, Marco Cassara (P) |
| 08-Mar | Mosta | vs | San Gwann | 2-0 | Nicholas Strickland, Nicholas Mifsud |
| 08-Mar | St. Andrews | vs | Zabbar SP | 3-0 | Zack Ebejer, Sean Gatt, Timothy Cachia |
| 08-Mar | Melita | vs | Floriana | 0-0 |
* Match abandoned on October 27 and resumed on November 9
Remaining matches were initially postponed and later cancelled following a decision by the MFA Executive Committee to end all competitions on April 29 due to the COVID-19 pandemic.