| Date | Home | vs | Away | Result | Scorers |
| 23-Nov | Kirkop U. | vs | Balzan | 0-2 | Gabriel Diego Farrugia, Sheldon Briffa |
| 24-Nov | Hamrun S. | vs | Valletta | 1-1 | Isaiah Micallef (V); Jamie Cutajar (H) |
| 24-Nov | San Gwann | vs | Pieta' H. | 1-1 | Dale Mifsud (SG); Zean Leonardi (P) |
| 24-Nov | Melita | vs | St. Andrews | 1-1 | Sebastian Cassar Torreggiani (SA); Andrew Sultana (M) |
| 30-Nov | Valletta | vs | Balzan | 4-0 | Antheos Spiteri, Zachary Miguel Chetuti, Daniel Letherby, Isaiah Micallef |
| 30-Nov | Pieta' H. | vs | St. Andrews | 2-1 | Jed Valletta (SA); Zean Leonardi, Jamie Scerri (P) |
| 01-Dec | Hamrun S. | vs | Melita | 2-2 | Leon Borg, Bjorn Buhagiar (H); Vinay Bharwani, Mattia Comes (M) |
| 01-Dec | San Gwann | vs | Kirkop U. | 5-0 | Andrea Zammit (3), Isaac Spiteri, Nathan Sultana |
| 08-Dec | St. Andrews | vs | Hamrun S. | 2-1 | Sebastian Cassar Torregiani, Nicholas Galea (SA); Bjorn Buhagiar (H) |
| 21-Dec | Balzan | vs | Pieta' H. | 2-1 | Luca Gatt (P); Gabriel Diego Farrugia, Jake Jovanovski (B) |
| 22-Dec | Melita | vs | San Gwann | 1-5 | Nathan Sultana, Andrea Zammit (2), Dale Mifsud, Aiden Vella (SG); Mattia Comes (M) |
| 22-Dec | Kirkop U. | vs | Valletta | 1-0 | Miguel Calleja |
| 04-Jan | Hamrun S. | vs | San Gwann | 1-1 | Shaisen Attard (H); James Vella (SG) |
| 05-Jan | St. Andrews | vs | Valletta | 1-0 | Jed Valletta |
| 05-Jan | Balzan | vs | Melita | 3-1 | Miguel Busuttil, Gabriel Diego Farrugia, Sheldon Briffa (B); Jaden Cuschieri (M) |
| 05-Jan | Pieta' H. | vs | Kirkop U. | 5-2 | Neil Buttigieg (3), Luca Gatt, Jamie Scerri (P); Andre Sultana, Kieron Camilleri (K) |
| 11-Jan | Melita | vs | Pieta' H. | 1-7 | Jamie Scerri (2), Neil Buttigieg (4), Brooklyn Borg (P); Mattia Comes (M) |
| 12-Jan | St. Andrews | vs | Balzan | 3-2 | Miguel Busuttil, Eric Atkins (B); Jed Valletta, Sebastian Cassar Torregiani, Russell Micallef (SA) |
| 12-Jan | Kirkop U. | vs | Hamrun S. | 1-4 | Jake Borg (2), Aiden Abdilla, Nikolai Micallef (H); Matthias Bugeja (K) |
| 12-Jan | Valletta | vs | San Gwann | 1-0 | Sheldon Mackay |
| 25-Jan | Hamrun S. | vs | Balzan | 4-0 | Jake Borg, Nathan Muscat, Alistair Aquilina, Jamie Cutajar |
| 25-Jan | San Gwann | vs | St. Andrews | 3-1 | Benjamin Hili, Dale Mifsud, Andrea Zammit (SG); William James England (SA) |
| 25-Jan | Kirkop U. | vs | Melita | 0-2 | Kieran Spiteri Shaw, Mattia Comes |
| 26-Jan | Pieta' H. | vs | Valletta | 1-2 | Matthew Pulis, Deacon Abela (V); Zean Leonardi (P) |
| 01-Feb | Balzan | vs | San Gwann | 0-3 | Nathan Sultana, Andrea Zammit, Dale Mifsud |
| 02-Feb | St. Andrews | vs | Kirkop U. | 3-0 | Nicholas Galea, Jed Valletta, William James England |
| 02-Feb | Pieta' H. | vs | Hamrun S. | 1-1 | Jamie Cutajar (H); Neil Buttigieg (P) |
| 02-Feb | Melita | vs | Valletta | 2-3 | Jaden Cuschieri, Mattia Comes (M); Deacon Abela, Sheldon Mackay, Isaiah Micallef (V) |
| 10-Feb | St. Andrews | vs | Melita | 2-0 | Nicholas Galea, Sebastian Cassar Torregiani |
| 10-Feb | Valletta | vs | Hamrun S. | 0-0 | |
| 10-Feb | Pieta’ H. | vs | San Gwann | 1-2 | Dale Mifsud, Nathan Sultana (SG); Nigel Scerri (P) |
| 10-Feb | Balzan | vs | Kirkop U. | 1-0 | Sheldon Briffa |
| 29-Feb | Balzan | vs | Valletta | 0-1 | Gary Farrugia |
| 29-Feb | Kirkop U. | vs | San Gwann | 0-0 | |
| 01-Mar | St. Andrews | vs | Pieta' H. | 1-2 | Brooklyn Borg, Jamie Scerri (P); Matthew Bonnici (SA) |
| 01-Mar | Melita | vs | Hamrun S. | 1-2 | Alistair Aquilina, Jamie Cutajar (H); Mattia Comes (M) |
| 07-Mar | Hamrun S. | vs | St. Andrews | 0-1 | William James England |
| 07-Mar | San Gwann | vs | Melita | 5-1 | James Vella (3), Dale Mifsud, own goal (SG); Mattia Comes (M) |
| 08-Mar | Pieta' H. | vs | Balzan | 3-0 | Zean Loenardi, Neil Buttigieg, Luca Gatt |
| 08-Mar | Valletta | vs | Kirkop U. | 1-1 | Miguel Calleja (K); Sheldon Mackay (V) |
Remaining matches were initially postponed and later cancelled following a decision by the MFA Executive Committee to end all competitions on April 29 due to the COVID-19 pandemic.