| Matches by round |
| 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 |
| Match list: | By round By date Latest | Player stats: |
| R | Date | Home | Score | Away | Location | |
| 21 | 08/05/2010 | Birzebbuga SP | 1 - 2 | Gzira U. | Centenary Stadium | |
| 21 | 08/05/2010 | Zurrieq | 0 - 0 | Mellieha | Centenary Stadium | |
| 21 | 09/05/2010 | Gharghur | 1 - 4 | Lija A. | Centenary Stadium | |
| 21 | 09/05/2010 | Zebbug R. | 7 - 1 | Gozo | Centenary Stadium | |
| 21 | 10/05/2010 | St. Venera L. | 2 - 6 | St. Andrews | Centenary Stadium | |
| 21 | 10/05/2010 | Senglea A. | 1 - 2 | Rabat A. | Centenary Stadium |