| Matches by round |
| 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 |
| Match list: | By round By date Latest | Player stats: |
| R | Date | Home | Score | Away | Location | |
| 1 | 27/09/2009 | St. Andrews | 3 - 1 | Mellieha | Centenary Stadium | |
| 2 | 03/10/2009 | Lija A. | 2 - 2 | St. Andrews | Centenary Stadium | |
| 3 | 24/10/2009 | Zurrieq | 1 - 3 | St. Andrews | Centenary Stadium | |
| 4 | 01/11/2009 | St. Andrews | 2 - 0 | Rabat A. | Centenary Stadium | |
| 5 | 22/11/2009 | St. Andrews | 2 - 1 | Gozo | Centenary Stadium | |
| 6 | 06/12/2009 | St. Andrews | 2 - 0 | Gzira U. | Centenary Stadium | |
| 7 | 19/12/2009 | Birzebbuga SP | 2 - 2 | St. Andrews | Centenary Stadium | |
| 8 | 03/01/2010 | St. Andrews | 2 - 0 | Zebbug R. | Centenary Stadium | |
| 9 | 17/01/2010 | Senglea A. | 1 - 1 | St. Andrews | Centenary Stadium | |
| 10 | 30/01/2010 | St. Andrews | 3 - 0 | St. Venera L. | Centenary Stadium | |
| 11 | 06/02/2010 | Gharghur | 0 - 3 | St. Andrews | Centenary Stadium | |
| 12 | 13/02/2010 | Mellieha | 0 - 2 | St. Andrews | Centenary Stadium | |
| 13 | 20/02/2010 | St. Andrews | 2 - 1 | Lija A. | Centenary Stadium | |
| 14 | 27/02/2010 | St. Andrews | 0 - 0 | Zurrieq | Centenary Stadium | |
| 15 | 07/03/2010 | Rabat A. | 1 - 2 | St. Andrews | Centenary Stadium | |
| 16 | 19/03/2010 | Gozo | 2 - 2 | St. Andrews | Gozo Stadium | |
| 17 | 03/04/2010 | Gzira U. | 1 - 0 | St. Andrews | Centenary Stadium | |
| 18 | 11/04/2010 | St. Andrews | 0 - 3 | Birzebbuga SP | Centenary Stadium | |
| 19 | 25/04/2010 | Zebbug R. | 1 - 1 | St. Andrews | Centenary Stadium | |
| 20 | 02/05/2010 | St. Andrews | 0 - 0 | Senglea A. | Centenary Stadium | |
| 21 | 10/05/2010 | St. Venera L. | 2 - 6 | St. Andrews | Centenary Stadium | |
| 22 | 16/05/2010 | St. Andrews | 4 - 1 | Gharghur | Centenary Stadium |