| Matches by round |
| 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 |
| Match list: | By round By date Latest | Player stats: |
| R | Date | Home | Score | Away | Location | |
| 1 | 26/09/2010 | Santa Lucia | 0 - 2 | Gudja U. | Centenary Stadium | |
| 1 | 26/09/2010 | Siggiewi | 2 - 1 | Mtarfa | Centenary Stadium | |
| 1 | 29/09/2010 | Mdina K. | 4 - 0 | Marsaskala | Centenary Stadium | |
| 1 | 29/09/2010 | Xghajra T. | 0 - 3 | Attard | Centenary Stadium | |
| 1 | 04/10/2010 | Swieqi U. | 1 - 1 | Qrendi | Centenary Stadium |