| Matches by round |
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| Match list: | By round By date Latest | Player stats: |
| R | Date | Home | Score | Away | Location | |
| 1 | 26/09/2010 | Siggiewi | 2 - 1 | Mtarfa | Centenary Stadium | |
| 2 | 05/10/2010 | Mtarfa | 1 - 1 | Mdina K. | Centenary Stadium | |
| 3 | 18/10/2010 | Xghajra T. | 2 - 1 | Mtarfa | Centenary Stadium | |
| 4 | 29/10/2010 | Mtarfa | 0 - 2 | Swieqi U. | Centenary Stadium | |
| 6 | 07/11/2010 | Sta. Venera L. | 1 - 0 | Mtarfa | Centenary Stadium | |
| 7 | 19/11/2010 | Mtarfa | 2 - 0 | Qrendi | Centenary Stadium | |
| 8 | 29/11/2010 | Attard | 2 - 0 | Mtarfa | Centenary Stadium | |
| 9 | 08/12/2010 | Mtarfa | 1 - 1 | Marsaskala | Centenary Stadium | |
| 10 | 19/12/2010 | Mtarfa | 1 - 1 | Santa Lucia | Centenary Stadium | |
| 11 | 02/01/2011 | Gudja U. | 3 - 0 | Mtarfa | Centenary Stadium | |
| 12 | 23/01/2011 | Mtarfa | 0 - 2 | Siggiewi | Centenary Stadium | |
| 13 | 01/02/2011 | Mdina K. | 1 - 1 | Mtarfa | Centenary Stadium | |
| 14 | 10/02/2011 | Mtarfa | 3 - 1 | Xghajra T. | Centenary Stadium | |
| 15 | 20/02/2011 | Swieqi U. | 2 - 0 | Mtarfa | Centenary Stadium | |
| 17 | 04/03/2011 | Mtarfa | 0 - 1 | Sta. Venera L. | Centenary Stadium | |
| 18 | 18/03/2011 | Qrendi | 2 - 2 | Mtarfa | Centenary Stadium | |
| 19 | 27/03/2011 | Mtarfa | 0 - 1 | Attard | Centenary Stadium | |
| 20 | 08/04/2011 | Marsaskala | 0 - 1 | Mtarfa | Centenary Stadium | |
| 21 | 23/04/2011 | Santa Lucia | 0 - 0 | Mtarfa | Centenary Stadium | |
| 22 | 01/05/2011 | Mtarfa | 1 - 1 | Gudja U. | Centenary Stadium |