| Matches by round |
| 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 |
| Match list: | By round By date Latest | Player stats: |
| R | Date | Home | Score | Away | Location | |
| 2 | 04/10/2010 | Sta. Venera L. | 2 - 0 | Santa Lucia | Centenary Stadium | |
| 3 | 14/10/2010 | Qrendi | 1 - 2 | Sta. Venera L. | Centenary Stadium | |
| 4 | 22/10/2010 | Sta. Venera L. | 2 - 0 | Attard | Centenary Stadium | |
| 5 | 29/10/2010 | Marsaskala | 0 - 2 | Sta. Venera L. | Centenary Stadium | |
| 6 | 07/11/2010 | Sta. Venera L. | 1 - 0 | Mtarfa | Centenary Stadium | |
| 7 | 19/11/2010 | Gudja U. | 3 - 1 | Sta. Venera L. | Centenary Stadium | |
| 8 | 28/11/2010 | Sta. Venera L. | 3 - 0 | Siggiewi | Centenary Stadium | |
| 9 | 05/12/2010 | Mdina K. | 1 - 0 | Sta. Venera L. | Centenary Stadium | |
| 10 | 12/12/2010 | Sta. Venera L. | 3 - 1 | Xghajra T. | Centenary Stadium | |
| 11 | 14/01/2011 | Swieqi U. | 1 - 4 | Sta. Venera L. | Centenary Stadium | |
| 13 | 28/01/2011 | Santa Lucia | 0 - 3 | Sta. Venera L. | Centenary Stadium | |
| 14 | 04/02/2011 | Sta. Venera L. | 2 - 0 | Qrendi | Centenary Stadium | |
| 15 | 13/02/2011 | Attard | 0 - 1 | Sta. Venera L. | Centenary Stadium | |
| 16 | 25/02/2011 | Sta. Venera L. | 3 - 2 | Marsaskala | Centenary Stadium | |
| 17 | 04/03/2011 | Mtarfa | 0 - 1 | Sta. Venera L. | Centenary Stadium | |
| 18 | 18/03/2011 | Sta. Venera L. | 1 - 1 | Gudja U. | Centenary Stadium | |
| 19 | 25/03/2011 | Siggiewi | 2 - 1 | Sta. Venera L. | Centenary Stadium | |
| 20 | 31/03/2011 | Sta. Venera L. | 2 - 0 | Mdina K. | Centenary Stadium | |
| 21 | 10/04/2011 | Xghajra T. | 0 - 1 | Sta. Venera L. | Centenary Stadium | |
| 22 | 23/04/2011 | Sta. Venera L. | 2 - 1 | Swieqi U. | Centenary Stadium |