| R | Date | Home | Score | Away | Location | |
| 21 | 29/04/2006 | Gzira U. | 0 - 1 | Dingli S. | Centenary Stadium | |
| 21 | 29/04/2006 | Mellieha | 0 - 1 | Zebbug R. | Centenary Stadium | |
| 21 | 30/04/2006 | Melita | 0 - 2 | Vittoriosa S. | Centenary Stadium | |
| 21 | 30/04/2006 | Balzan Y. | 7 - 0 | Gharghur | Centenary Stadium | |
| 21 | 01/05/2006 | Qormi | 3 - 0 | Gozo | Centenary Stadium | |
| 21 | 01/05/2006 | Gudja U. | 3 - 2 | Attard | Centenary Stadium |
| Created on 09/05/2006 with LeaguePad |
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| Balzan Y. Matches |
| Dingli S. Matches |
| Gharghur Matches |
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| Gudja U. Matches |
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| Mellieha Matches |
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| Vittoriosa S. Matches |
| Zebbug R. Matches |