| Matches by round |
| 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 |
| Match list: | By round By date Latest | Player stats: |
| R | Date | Home | Score | Away | Location | |
| 4 | 15/10/2010 | Birkirkara | 2 - 2 | Valletta | National Stadium | |
| 4 | 17/10/2010 | Hamrun S. | 1 - 2 | Floriana | National Stadium | |
| 4 | 17/10/2010 | Marsaxlokk | 2 - 2 | Hibernians | National Stadium | |
| 4 | 18/10/2010 | Vittoriosa S. | 0 - 1 | Sliema W. | V. Tedesco Stadium | |
| 4 | 18/10/2010 | Qormi | 2 - 1 | Tarxien R. | V. Tedesco Stadium |