| Matches by round |
| 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 |
| Match list: | By round By date Latest | Player stats: |
| R | Date | Home | Score | Away | Location | |
| 1 | 13/09/2010 | Sliema W. | 1 - 4 | Birkirkara | National Stadium | |
| 2 | 19/09/2010 | Marsaxlokk | 0 - 0 | Sliema W. | National Stadium | |
| 3 | 26/09/2010 | Sliema W. | 3 - 1 | Hamrun S. | National Stadium | |
| 4 | 18/10/2010 | Vittoriosa S. | 0 - 1 | Sliema W. | V. Tedesco Stadium | |
| 5 | 25/10/2010 | Sliema W. | 0 - 0 | Qormi | V. Tedesco Stadium | |
| 6 | 31/10/2010 | Tarxien R. | 2 - 1 | Sliema W. | Hibernians Stadium | |
| 7 | 05/11/2010 | Valletta | 4 - 0 | Sliema W. | V. Tedesco Stadium | |
| 8 | 20/11/2010 | Sliema W. | 0 - 1 | Floriana | Hibernians Stadium | |
| 9 | 27/11/2010 | Hibernians | 0 - 0 | Sliema W. | National Stadium | |
| 10 | 05/12/2010 | Birkirkara | 2 - 2 | Sliema W. | National Stadium | |
| 11 | 12/12/2010 | Sliema W. | 1 - 1 | Marsaxlokk | Hibernians Stadium | |
| 12 | 17/12/2010 | Hamrun S. | 3 - 2 | Sliema W. | V. Tedesco Stadium | |
| 13 | 09/01/2011 | Sliema W. | 4 - 3 | Vittoriosa S. | Hibernians Stadium | |
| 14 | 15/01/2011 | Qormi | 0 - 0 | Sliema W. | Hibernians Stadium | |
| 15 | 24/01/2011 | Sliema W. | 1 - 1 | Tarxien R. | V. Tedesco Stadium | |
| 16 | 29/01/2011 | Sliema W. | 1 - 4 | Valletta | National Stadium | |
| 17 | 06/02/2011 | Floriana | 0 - 1 | Sliema W. | Hibernians Stadium | |
| 18 | 13/02/2011 | Sliema W. | 4 - 0 | Hibernians | V. Tedesco Stadium | |
| 19 | 21/02/2011 | Qormi | 0 - 4 | Sliema W. | Hibernians Stadium | |
| 20 | 04/03/2011 | Sliema W. | 0 - 1 | Hibernians | Hibernians Stadium | |
| 21 | 12/03/2011 | Vittoriosa S. | 1 - 2 | Sliema W. | Hibernians Stadium | |
| 22 | 02/04/2011 | Sliema W. | 4 - 1 | Qormi | Hibernians Stadium | |
| 23 | 10/04/2011 | Hibernians | 2 - 3 | Sliema W. | National Stadium | |
| 24 | 16/04/2011 | Sliema W. | 2 - 0 | Vittoriosa S. | Hibernians Stadium |