| R | Date | Home | Score | Away | Location | |
| 1 | 02/10/2005 | Sirens | 2 - 0 | Kalkara | Centenary Stadium | |
| 3 | 21/10/2005 | Kalkara | 0 - 1 | Fgura U. | Centenary Stadium | |
| 4 | 30/10/2005 | Kalkara | 1 - 1 | Zejtun C. | Centenary Stadium | |
| 5 | 15/11/2005 | Luqa SA | 1 - 3 | Kalkara | Centenary Stadium | |
| 6 | 28/11/2005 | Kalkara | 0 - 4 | Zurrieq | Centenary Stadium | |
| 7 | 10/12/2005 | Sta. Venera L. | 2 - 1 | Kalkara | Centenary Stadium | |
| 8 | 06/01/2006 | Kalkara | 1 - 1 | Pembroke A. | Centenary Stadium | |
| 9 | 20/01/2006 | Sta. Lucia | 2 - 0 | Kalkara | Centenary Stadium | |
| 10 | 03/02/2006 | Kalkara | 1 - 1 | Mgarr U. | Centenary Stadium | |
| 11 | 12/02/2006 | Rabat A. | 1 - 2 | Kalkara | Centenary Stadium | |
| 12 | 28/02/2006 | Kalkara | 1 - 0 | Ghaxaq | Centenary Stadium | |
| 13 | 12/03/2006 | Birzebbuga SP | 2 - 0 | Kalkara | Centenary Stadium | |
| 14 | 26/03/2006 | Kalkara | 0 - 0 | Xghajra T. | Centenary Stadium | |
| 15 | 02/04/2006 | Ta Xbiex | 0 - 6 | Kalkara | Centenary Stadium | |
| 16 | 21/04/2006 | Kalkara | 2 - 3 | Siggiewi | Centenary Stadium | |
| 17 | 30/04/2006 | Kirkop U. | 1 - 1 | Kalkara | Centenary Stadium |
| Created on 07/05/2006 with LeaguePad |
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| Team pages |
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| Fgura U. Matches |
| Ghaxaq Matches |
| Kalkara Matches |
| Kirkop U. Matches |
| Luqa SA Matches |
| Mgarr U. Matches |
| Pembroke A. Matches |
| Rabat A. Matches |
| Siggiewi Matches |
| Sirens Matches |
| Sta. Lucia Matches |
| Sta. Venera L. Matches |
| Ta Xbiex Matches |
| Xghajra T. Matches |
| Zejtun C. Matches |
| Zurrieq Matches |