| R | Date | Home | Score | Away | Location | |
| 1 | 30/09/2005 | Siggiewi | 1 - 0 | Luqa SA | Centenary Stadium | |
| 2 | 13/10/2005 | Zurrieq | 1 - 2 | Siggiewi | Centenary Stadium | |
| 3 | 24/10/2005 | Siggiewi | 1 - 1 | Sta. Venera L. | Centenary Stadium | |
| 4 | 08/11/2005 | Pembroke A. | 0 - 1 | Siggiewi | Centenary Stadium | |
| 5 | 29/11/2005 | Siggiewi | 1 - 2 | Sta. Lucia | Centenary Stadium | |
| 6 | 04/12/2005 | Mgarr U. | 0 - 1 | Siggiewi | Centenary Stadium | |
| 7 | 13/12/2005 | Siggiewi | 0 - 2 | Rabat A. | Centenary Stadium | |
| 8 | 13/01/2006 | Ghaxaq | 2 - 1 | Siggiewi | Centenary Stadium | |
| 9 | 27/01/2006 | Siggiewi | 0 - 1 | Birzebbuga SP | Centenary Stadium | |
| 10 | 10/02/2006 | Xghajra T. | 1 - 2 | Siggiewi | Centenary Stadium | |
| 11 | 19/02/2006 | Siggiewi | 7 - 3 | Ta Xbiex | Centenary Stadium | |
| 12 | 05/03/2006 | Fgura U. | 1 - 3 | Siggiewi | Centenary Stadium | |
| 13 | 24/03/2006 | Kirkop U. | 1 - 3 | Siggiewi | Centenary Stadium | |
| 14 | 01/04/2006 | Siggiewi | 1 - 2 | Sirens | Centenary Stadium | |
| 16 | 21/04/2006 | Kalkara | 2 - 3 | Siggiewi | Centenary Stadium | |
| 17 | 30/04/2006 | Siggiewi | 3 - 4 | Zejtun C. | Centenary Stadium |
| Created on 07/05/2006 with LeaguePad |
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| League tables |
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| Team pages |
| Birzebbuga SP Matches |
| Fgura U. Matches |
| Ghaxaq Matches |
| Kalkara Matches |
| Kirkop U. Matches |
| Luqa SA Matches |
| Mgarr U. Matches |
| Pembroke A. Matches |
| Rabat A. Matches |
| Siggiewi Matches |
| Sirens Matches |
| Sta. Lucia Matches |
| Sta. Venera L. Matches |
| Ta Xbiex Matches |
| Xghajra T. Matches |
| Zejtun C. Matches |
| Zurrieq Matches |