| R | Date | Home | Score | Away | Location | |
| Round 1 | ||||||
| 24/09/2005 | Mellieha | 1 - 1 | Vittoriosa S. | Centenary Stadium | ||
| 24/09/2005 | Gzira U. | 1 - 2 | Balzan Y. | Centenary Stadium | ||
| 25/09/2005 | Qormi | 2 - 2 | Zebbug R. | Centenary Stadium | ||
| 25/09/2005 | Dingli S. | 3 - 1 | Gudja U. | Centenary Stadium | ||
| 25/09/2005 | Gozo | 0 - 0 | Gharghur | Gozo Stadium | ||
| 26/09/2005 | Attard | 1 - 1 | Melita | Centenary Stadium | ||
| Round 2 | ||||||
| 01/10/2005 | Gudja U. | 2 - 2 | Gzira U. | Centenary Stadium | ||
| 01/10/2005 | Vittoriosa S. | 3 - 3 | Qormi | Centenary Stadium | ||
| 02/10/2005 | Balzan Y. | 2 - 0 | Mellieha | Centenary Stadium | ||
| 02/10/2005 | Zebbug R. | 1 - 0 | Attard | Centenary Stadium | ||
| 03/10/2005 | Dingli S. | 1 - 1 | Gozo | Centenary Stadium | ||
| 03/10/2005 | Melita | 1 - 2 | Gharghur | Centenary Stadium | ||
| Round 3 | ||||||
| 09/10/2005 | Mellieha | 0 - 0 | Qormi | Centenary Stadium | ||
| 09/10/2005 | Balzan Y. | 1 - 0 | Gudja U. | Centenary Stadium | ||
| 09/10/2005 | Gozo | 2 - 0 | Gzira U. | Gozo Stadium | ||
| 10/10/2005 | Attard | 0 - 2 | Vittoriosa S. | Centenary Stadium | ||
| 10/10/2005 | Gharghur | 0 - 0 | Zebbug R. | Centenary Stadium | ||
| 15/10/2005 | Dingli S. | 0 - 0 | Melita | Centenary Stadium | ||
| Round 4 | ||||||
| 15/10/2005 | Qormi | 2 - 1 | Attard | Centenary Stadium | ||
| 16/10/2005 | Gudja U. | 0 - 3 | Mellieha | Centenary Stadium | ||
| 16/10/2005 | Balzan Y. | 2 - 0 | Gozo | Centenary Stadium | ||
| 22/10/2005 | Vittoriosa S. | 1 - 0 | Gharghur | Centenary Stadium | ||
| 22/10/2005 | Melita | 3 - 2 | Gzira U. | Centenary Stadium | ||
| 23/10/2005 | Zebbug R. | 0 - 0 | Dingli S. | Centenary Stadium | ||
| Round 5 | ||||||
| 23/10/2005 | Mellieha | 3 - 0 | Attard | Centenary Stadium | ||
| 23/10/2005 | Gozo | 1 - 1 | Gudja U. | Gozo Stadium | ||
| 31/10/2005 | Gharghur | 0 - 2 | Qormi | Centenary Stadium | ||
| 31/10/2005 | Balzan Y. | 0 - 2 | Melita | Centenary Stadium | ||
| 06/11/2005 | Dingli S. | 0 - 0 | Vittoriosa S. | Centenary Stadium | ||
| 06/11/2005 | Gzira U. | 0 - 0 | Zebbug R. | Centenary Stadium | ||
| Round 6 | ||||||
| 07/11/2005 | Mellieha | 3 - 1 | Gozo | Centenary Stadium | ||
| 07/11/2005 | Attard | 1 - 0 | Gharghur | Centenary Stadium | ||
| 11/11/2005 | Melita | 0 - 2 | Gudja U. | Centenary Stadium | ||
| 11/11/2005 | Qormi | 3 - 1 | Dingli S. | Centenary Stadium | ||
| 13/11/2005 | Zebbug R. | 1 - 1 | Balzan Y. | Centenary Stadium | ||
| 13/11/2005 | Vittoriosa S. | 0 - 0 | Gzira U. | Centenary Stadium | ||
| Round 7 | ||||||
| 18/11/2005 | Mellieha | 4 - 3 | Gharghur | Centenary Stadium | ||
| 18/11/2005 | Dingli S. | 7 - 0 | Attard | Centenary Stadium | ||
| 21/11/2005 | Melita | 4 - 0 | Gozo | Centenary Stadium | ||
| 21/11/2005 | Gudja U. | 0 - 1 | Zebbug R. | Centenary Stadium | ||
| 22/11/2005 | Gzira U. | 1 - 3 | Qormi | Centenary Stadium | ||
| 22/11/2005 | Balzan Y. | 0 - 4 | Vittoriosa S. | Centenary Stadium | ||
| Round 8 | ||||||
| 26/11/2005 | Gharghur | 1 - 2 | Dingli S. | Centenary Stadium | ||
| 26/11/2005 | Melita | 2 - 0 | Mellieha | Centenary Stadium | ||
| 27/11/2005 | Attard | 0 - 2 | Gzira U. | Centenary Stadium | ||
| 27/11/2005 | Vittoriosa S. | 1 - 1 | Gudja U. | Centenary Stadium | ||
| 27/11/2005 | Gozo | 0 - 0 | Zebbug R. | Gozo Stadium | ||
| 04/12/2005 | Qormi | 1 - 1 | Balzan Y. | Centenary Stadium | ||
| Round 9 | ||||||
| 04/12/2005 | Mellieha | 1 - 1 | Dingli S. | Centenary Stadium | ||
| 08/12/2005 | Melita | 1 - 2 | Zebbug R. | Centenary Stadium | ||
| 08/12/2005 | Gzira U. | 1 - 0 | Gharghur | Centenary Stadium | ||
| 11/12/2005 | Balzan Y. | 3 - 0 | Attard | Centenary Stadium | ||
| 11/12/2005 | Vittoriosa S. | 2 - 0 | Gozo | Gozo Stadium | ||
| 13/12/2005 | Gudja U. | 1 - 2 | Qormi | Centenary Stadium | ||
| Round 10 | ||||||
| 13/12/2005 | Dingli S. | 1 - 1 | Gzira U. | Centenary Stadium | ||
| 07/01/2006 | Zebbug R. | 1 - 1 | Mellieha | Centenary Stadium | ||
| 07/01/2006 | Vittoriosa S. | 4 - 2 | Melita | Centenary Stadium | ||
| 08/01/2006 | Gharghur | 1 - 3 | Balzan Y. | Centenary Stadium | ||
| 08/01/2006 | Attard | 0 - 4 | Gudja U. | Centenary Stadium | ||
| 08/01/2006 | Gozo | 1 - 3 | Qormi | Gozo Stadium | ||
| Round 11 | ||||||
| 14/01/2006 | Mellieha | 1 - 1 | Gzira U. | Centenary Stadium | ||
| 14/01/2006 | Zebbug R. | 0 - 1 | Vittoriosa S. | Centenary Stadium | ||
| 15/01/2006 | Balzan Y. | 1 - 2 | Dingli S. | Centenary Stadium | ||
| 15/01/2006 | Melita | 0 - 1 | Qormi | Centenary Stadium | ||
| 21/01/2006 | Gudja U. | 1 - 0 | Gharghur | Centenary Stadium | ||
| 22/01/2006 | Gozo | 3 - 0 | Attard | Gozo Stadium | ||
| Round 12 | ||||||
| 21/01/2006 | Vittoriosa S. | 1 - 2 | Mellieha | Centenary Stadium | ||
| 22/01/2006 | Balzan Y. | 0 - 1 | Gzira U. | Centenary Stadium | ||
| 22/01/2006 | Zebbug R. | 1 - 2 | Qormi | Centenary Stadium | ||
| 28/01/2006 | Gudja U. | 0 - 1 | Dingli S. | Centenary Stadium | ||
| 28/01/2006 | Melita | 1 - 2 | Attard | Centenary Stadium | ||
| 29/01/2006 | Gharghur | 6 - 3 | Gozo | Centenary Stadium | ||
| Round 13 | ||||||
| 29/01/2006 | Qormi | 1 - 2 | Vittoriosa S. | Centenary Stadium | ||
| 04/02/2006 | Mellieha | 3 - 1 | Balzan Y. | Centenary Stadium | ||
| 04/02/2006 | Gzira U. | 1 - 1 | Gudja U. | Centenary Stadium | ||
| 05/02/2006 | Attard | 0 - 0 | Zebbug R. | Centenary Stadium | ||
| 05/02/2006 | Gharghur | 0 - 0 | Melita | Centenary Stadium | ||
| 05/02/2006 | Gozo | 1 - 1 | Dingli S. | Gozo Stadium | ||
| Round 14 | ||||||
| 10/02/2006 | Qormi | 1 - 3 | Mellieha | Centenary Stadium | ||
| 10/02/2006 | Gudja U. | 3 - 2 | Balzan Y. | Centenary Stadium | ||
| 12/02/2006 | Vittoriosa S. | 1 - 1 | Attard | Centenary Stadium | ||
| 12/02/2006 | Gzira U. | 1 - 1 | Gozo | Centenary Stadium | ||
| 18/02/2006 | Zebbug R. | 1 - 0 | Gharghur | Centenary Stadium | ||
| 18/02/2006 | Melita | 0 - 0 | Dingli S. | Centenary Stadium | ||
| Round 15 | ||||||
| 19/02/2006 | Attard | 0 - 5 | Qormi | Centenary Stadium | ||
| 19/02/2006 | Mellieha | 2 - 0 | Gudja U. | Centenary Stadium | ||
| 26/02/2006 | Gharghur | 1 - 2 | Vittoriosa S. | Centenary Stadium | ||
| 26/02/2006 | Gzira U. | 1 - 6 | Melita | Centenary Stadium | ||
| 26/02/2006 | Gozo | 3 - 1 | Balzan Y. | Centenary Stadium | ||
| 04/03/2006 | Dingli S. | 1 - 0 | Zebbug R. | Centenary Stadium | ||
| Round 16 | ||||||
| 04/03/2006 | Attard | 2 - 2 | Mellieha | Centenary Stadium | ||
| 05/03/2006 | Qormi | 3 - 0 | Gharghur | Centenary Stadium | ||
| 05/03/2006 | Gudja U. | 0 - 0 | Gozo | Centenary Stadium | ||
| 11/03/2006 | Melita | 3 - 1 | Balzan Y. | Centenary Stadium | ||
| 11/03/2006 | Vittoriosa S. | 2 - 1 | Dingli S. | Centenary Stadium | ||
| 12/03/2006 | Zebbug R. | 1 - 0 | Gzira U. | Centenary Stadium | ||
| Round 17 | ||||||
| 12/03/2006 | Gharghur | 0 - 1 | Attard | Centenary Stadium | ||
| 12/03/2006 | Gozo | 2 - 1 | Mellieha | Gozo Stadium | ||
| 18/03/2006 | Gudja U. | 2 - 2 | Melita | Centenary Stadium | ||
| 18/03/2006 | Dingli S. | 0 - 0 | Qormi | Centenary Stadium | ||
| 19/03/2006 | Balzan Y. | 3 - 1 | Zebbug R. | Centenary Stadium | ||
| 19/03/2006 | Gzira U. | 1 - 2 | Vittoriosa S. | Centenary Stadium | ||
| Round 18 | ||||||
| 25/03/2006 | Gharghur | 0 - 6 | Mellieha | Centenary Stadium | ||
| 25/03/2006 | Attard | 2 - 0 | Dingli S. | Centenary Stadium | ||
| 26/03/2006 | Zebbug R. | 0 - 1 | Gudja U. | Centenary Stadium | ||
| 26/03/2006 | Qormi | 5 - 2 | Gzira U. | Centenary Stadium | ||
| 26/03/2006 | Gozo | 2 - 1 | Melita | Gozo Stadium | ||
| 31/03/2006 | Vittoriosa S. | 1 - 2 | Balzan Y. | Centenary Stadium | ||
| Round 19 | ||||||
| 31/03/2006 | Dingli S. | 3 - 0 | Gharghur | Centenary Stadium | ||
| 02/04/2006 | Mellieha | 3 - 1 | Melita | Centenary Stadium | ||
| 02/04/2006 | Gzira U. | 3 - 0 | Attard | Centenary Stadium | ||
| 09/04/2006 | Gudja U. | 0 - 2 | Vittoriosa S. | Centenary Stadium | ||
| 09/04/2006 | Balzan Y. | 0 - 2 | Qormi | Centenary Stadium | ||
| 10/04/2006 | Zebbug R. | 0 - 1 | Gozo | Centenary Stadium | ||
| Round 20 | ||||||
| 10/04/2006 | Dingli S. | 0 - 0 | Mellieha | Centenary Stadium | ||
| 22/04/2006 | Zebbug R. | 0 - 2 | Melita | Centenary Stadium | ||
| 22/04/2006 | Gharghur | 3 - 4 | Gzira U. | Centenary Stadium | ||
| 23/04/2006 | Attard | 2 - 1 | Balzan Y. | Centenary Stadium | ||
| 23/04/2006 | Qormi | 2 - 1 | Gudja U. | Centenary Stadium | ||
| 23/04/2006 | Gozo | 0 - 0 | Vittoriosa S. | Gozo Stadium | ||
| Round 21 | ||||||
| 29/04/2006 | Gzira U. | 0 - 1 | Dingli S. | Centenary Stadium | ||
| 29/04/2006 | Mellieha | 0 - 1 | Zebbug R. | Centenary Stadium | ||
| 30/04/2006 | Melita | 0 - 2 | Vittoriosa S. | Centenary Stadium | ||
| 30/04/2006 | Balzan Y. | 7 - 0 | Gharghur | Centenary Stadium | ||
| 01/05/2006 | Qormi | 3 - 0 | Gozo | Centenary Stadium | ||
| 01/05/2006 | Gudja U. | 3 - 2 | Attard | Centenary Stadium | ||
| Round 22 | ||||||
| 06/05/2006 | Gzira U. | 1 - 0 | Mellieha | Centenary Stadium | ||
| 06/05/2006 | Vittoriosa S. | 0 - 0 | Zebbug R. | Centenary Stadium | ||
| 07/05/2006 | Dingli S. | 2 - 2 | Balzan Y. | Centenary Stadium | ||
| 07/05/2006 | Qormi | 2 - 0 | Melita | Centenary Stadium | ||
| 08/05/2006 | Gharghur | 0 - 2 | Gudja U. | Centenary Stadium | ||
| 08/05/2006 | Attard | 1 - 2 | Gozo | Centenary Stadium |
| Created on 09/05/2006 with LeaguePad |
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