| R | Date | Home | Score | Away | Location | |
| 1 | 11/08/2005 | Hamrun S. | 1 - 2 | Marsaxlokk | National Stadium | |
| 3 | 20/08/2005 | Hamrun S. | 2 - 4 | Pietà H. | National Stadium | |
| 2 | 25/08/2005 | Sliema W. | 4 - 1 | Hamrun S. | National Stadium | |
| 4 | 10/09/2005 | Hibernians | 1 - 0 | Hamrun S. | National Stadium | |
| 5 | 17/09/2005 | Floriana | 1 - 3 | Hamrun S. | National Stadium | |
| 6 | 28/09/2005 | Hamrun S. | 2 - 1 | Mosta | National Stadium | |
| 7 | 01/10/2005 | Birkirkara | 2 - 1 | Hamrun S. | National Stadium | |
| 8 | 17/10/2005 | Hamrun S. | 4 - 2 | Valletta | National Stadium | |
| 9 | 23/10/2005 | Msida SJ | 2 - 1 | Hamrun S. | National Stadium | |
| 10 | 30/10/2005 | Marsaxlokk | 4 - 3 | Hamrun S. | National Stadium | |
| 11 | 20/11/2005 | Hamrun S. | 1 - 1 | Sliema W. | V. Tedesco Stadium | |
| 12 | 14/12/2005 | Pietà H. | 2 - 3 | Hamrun S. | Centenary Stadium | |
| 13 | 18/12/2005 | Hamrun S. | 0 - 2 | Hibernians | National Stadium | |
| 14 | 07/01/2006 | Hamrun S. | 2 - 4 | Floriana | National Stadium | |
| 15 | 17/01/2006 | Mosta | 0 - 3 | Hamrun S. | Centenary Stadium | |
| 16 | 21/01/2006 | Hamrun S. | 0 - 6 | Birkirkara | National Stadium | |
| 17 | 05/02/2006 | Valletta | 1 - 2 | Hamrun S. | National Stadium | |
| 18 | 12/02/2006 | Hamrun S. | 0 - 2 | Msida SJ | Hibernians Ground | |
| 19 | 12/03/2006 | Floriana | 3 - 0 | Hamrun S. | Hibernians Ground | |
| 20 | 19/03/2006 | Hamrun S. | 3 - 5 | Mosta | Hibernians Ground | |
| 21 | 16/04/2006 | Hamrun S. | 0 - 2 | Pietà H. | National Stadium | |
| 22 | 21/04/2006 | Hamrun S. | 2 - 4 | Floriana | National Stadium | |
| 23 | 05/05/2006 | Hamrun S. | 0 - 0 | Mosta | National Stadium | |
| 24 | 13/05/2006 | Pietà H. | 1 - 1 | Hamrun S. | National Stadium |
| Created on 14/05/2006 with LeaguePad |
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| Floriana Matches |
| Hamrun S. Matches |
| Hibernians Matches |
| Marsaxlokk Matches |
| Mosta Matches |
| Msida SJ Matches |
| Pietà H. Matches |
| Sliema W. Matches |
| Valletta Matches |